The following information is a summary about Zyban. It is not intended to replace a doctor''s instructions.
(Zyban - BUPROPION sustained release - ORAL)
Swallow Zyban whole. Do not crush or chew them or the sustained activity of the drug will be destroyed and the chances of side effects occurring may be increased. Take as directed, usually twice daily for 7 to 12 weeks. Do not take more or less med than prescribed. Since Zyban can cause sleeplessness at first, it is best not to take near bedtime. It is advised to continue smoking for the first week after starting Zyban until it reaches higher levels in your blood. Do not smoke if using any nicotine products with Zyban. Too much nicotine can cause serious side effects.
Before taking Zyban tell your doctor if you have a history of seizures, head injury, brain tumor; heart, liver or kidney disease, an eating disorder or any mental conditions, diabetes or if you have any allergies. Limit or avoid consumption of alcoholic beverages; alcohol can increase your risk of seizures. Chronic alcohol users who suddenly stop the intake of alcohol while taking bupropion may increase the risk of having seizures. Suddenly stopping certain tranquilizers (e.g., diazepam, chlordiazepoxide) is not recommended because doing so may increase the risk of having seizures. Elderly patients may be more sensitive to the effects of Zyban. Tell your doctor if you are pregnant or plan to become pregnant before taking it. Zyban is excreted into breast milk. Because of the potential risk to the infant, BREAST-FEEDING WHILE USING Zyban IS NOT RECOMMENDED. Consult your doctor before breast-feeding.
Zyban is generally well tolerated. Dry mouth, headache, increased sweating, constipation, anxiety and fatigue may occur. If these effects persist or worsen, notify your doctor.
Take any missed dose as soon as possible but not if it is within 8 hours of the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not "double up" the dose.
Before taking Zyban tell your doctor of all nonprescription and prescription meds you may use especially MAO inhibitors (e.g., isocarboxazid, phenelzine, tranylcypromine, pargyline, selegiline, furazolidone), levodopa, theophylline, corticosteroids (e.g., prednisone), seizure meds, sedatives, ritonavir, tranquilizers/psychiatric drugs (e.g., chlorpromazine), other antidepressants (e.g., amitriptyline), salicylates (e.g., aspirin, salsalate), isoniazid, chlolinesterase inhibitors (e.g., tacrine, donepezil), morphine, and adrenaline-like drugs (e.g., pseudoephedrine). Excess caffeine intake can increase the chance of seizures with Zyban. Check all nonprescription/prescription drug labels for caffeine. Consult doctor or pharmacist. A certain product used to help quit smoking contains bupropion. Do not take that product while using this one.
Store at room temperature and keep away from moisture and sunlight. KEEP ZYBAN AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN.
For more information on Zyban, you can visit http://www.zyban.com.